Chromatography

The following section introduces some of the chromatographic methods we apply. It also features their principle of operation and some typical applications.

Gas Chromatography - Mass Spectrometry (GC-MS)

  • The combination of gas chromatography (GC) and mass spectrometry (MS) allows the separation of vaporizable mixed substances and the identification of individual organic components on the basis of the mass spectrum. Coupled with a head space injector or a thermo desorption device, the area of application expands to solid and/or non vaporizable samples.
  • Areas of Application: Qualitative and quantitative analyses of gas or fluid samples such as, for example, coatings solvents or the identification of unknown compounds in oil samples, determination of the emission of organic compounds such as, for example, materials in a car interior, monitoring of MAC threshold values through the analysis of air samples.

Preparative Liquid Chromatography (LC)

  • Preparative liquid chromatography enables the separation of large substance quantities.
  • Areas of Application: Batch comparison, isolation of relevant fractions (possibly in combination with a spectroscopic technique), extraction of reference substances.

High Performance Liquid Chromatography (HPLC)

  • HPLC separates and quantifies polar, volatile materials and allows substance identification by comparing of retention times with a reference. It is also suitable for the analysis of volatiles in aqueous or buffer solutions.
  • Areas of Application: Determination of aldehydes and ketones in automotive interior.